Publications by authors named "C de Grave"
Epidemiology of cardiovascular risk factors: Behavioural risk factors.
Arch Cardiovasc Dis
December 2024
Article Synopsis
- * A significant portion of the French population engages in unhealthy behaviors: one-third smoke, 71.7% don’t consume enough fruits and vegetables, and many fail to meet physical activity guidelines.
- * Although there are some improvements, like increased physical activity in men and reduced smoking rates, serious concerns remain, especially as women's health behaviors begin to mirror those of men, highlighting the need for enhanced prevention efforts.
Background: Hypertension is the most common chronic disease and a major modifiable risk factor for cardio-cerebrovascular and renal diseases. This study estimated the national burden of hypertension, defined as systolic blood pressure ≥140 mm Hg, on morbidity and mortality in 2021 in France.
Methods: For all diseases causally associated with hypertension (cardiovascular diseases, chronic kidney diseases, and dementia), the number and proportion of cases attributable to hypertension in adults aged ≥35 years were estimated using population attributable fractions.
Article Synopsis
- The study reviews the management and outcomes of stroke cases in France, revealing significant data from the year 2022 after nearly a decade of a national stroke plan.
- In total, 122,422 adults were hospitalized for stroke, with stark variations in care based on geographic and socioeconomic factors, and low rates of advanced treatments like mechanical thrombectomy.
- The findings indicate high mortality rates within a year post-stroke and call for improved prevention strategies, better public awareness of stroke symptoms, and enhanced accessibility to stroke care services.
Epidemiology of aortic and peripheral arterial diseases in France.
Arch Cardiovasc Dis
December 2024
Background: Peripheral arterial diseases (PADs) account for much of the morbidity and hospitalizations experienced by patients with cardiovascular disease. Epidemiological data on these diseases are lacking in France.
Aims: To describe the epidemiology of aortic diseases (aneurysm and dissection) and PADs in France in 2022.
Infrared probes are chemical moieties whose vibrational modes are used to obtain spectroscopic information about structural dynamics of complex systems; in particular, of biomacromolecules. Here, we explore the vibrational spectroscopy and dynamics of a reagent, 3-(4-azidophenyl)propiolonitrile (AzPPN), for selectively tagging thiols in protein environments with a multifunctional infrared probe containing both, an azide and a nitrile chromophore. The linear infrared spectrum of AzPPN is heavily perturbed in the antisymmetric azide stretching region as a result of accidental Fermi resonances.
View Article and Find Full Text PDF