Publications by authors named "C de Bedout"

Article Synopsis
  • Colombia lacks a specialized service for measuring antifungal blood levels, which is crucial for monitoring antifungal treatments.
  • The study aimed to develop and validate a high-performance liquid chromatography (HPLC) protocol to accurately quantify voriconazole blood levels.
  • The validated method shows good selectivity and sensitivity, making it an effective tool for monitoring patients undergoing voriconazole therapy.
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Invasive fungal diseases (IFD) contribute significantly to worldwide morbidity and mortality, but their frequency is not well-described in some countries. The present work describes the frequency of IFD in a specialized laboratory in Colombia. A retrospective, descriptive study was implemented between March 2009 and December 2015.

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Background: The yeasts species determination is fundamental not only for an accurate diagnosis but also for establishing a suitable patient treatment. We performed a concordance study of five methodologies for the species identification of oral isolates of in Colombia.

Methods: Sixty-seven isolates were tested by; API® 20C-AUX, Vitek®2 Compact, Vitek®MS, Microflex® and a molecular test (panfungal PCR and sequencing).

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is the causative agent of histoplasmosis and this fungus inhabits soils rich in phosphorus and nitrogen that are enriched with bird and bat manure. The replacement of organic matter in agroecosystems is necessary in the tropics, and the use of organic fertilizers has increased. Cases and outbreaks due to the presence of the fungus in these components have been reported.

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Objectives: Invasive candidiasis has a high impact on morbidity and mortality in hospitalised patients. Accurate and timely methods for identification of Candida spp. and determination of echinocandin susceptibility have become a priority for clinical microbiology laboratories.

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