Resistance training maintains physical function but does not prevent changes in body composition and biochemical markers after detraining in aging adults.

Objective: The objective of the present study was to analyze the effects of 10 weeks of resistance training (RT) and subsequent 4 weeks of detraining on physical function, body composition, and biochemical markers in aging adults.

Methods: The study sample was selected by convenience and consisted of 12 women with a mean age of 58 ± 7 years. Physical function [Latin-American Group of Development for Maturity (GDLAM) general index], body composition, total and fractional cholesterol, triglycerides, and glycemia were assessed before and after RT (10 weeks) and detraining (4 weeks).

Paternal Exercise Improves the Metabolic Health of Offspring via Epigenetic Modulation of the Germline.

Background/aims: Epigenetic regulation is considered the main molecular mechanism underlying the developmental origin of health and disease's (DOHAD) hypothesis. Previous studies that have investigated the role of paternal exercise on the metabolic health of the offspring did not control for the amount and intensity of the training or possible effects of adaptation to exercise and produced conflicting results regarding the benefits of parental exercise to the next generation. We employed a precisely regulated exercise regimen to study the transgenerational inheritance of improved metabolic health.

Offspring from trained male mice inherit improved muscle mitochondrial function through PPAR co-repressor modulation.

Unlabelled: Aim Investigate whether inheritance of improved skeletal muscle mitochondrial function and its association with glycemic control are multigenerational benefits of exercise.

Main Methods: Male Swiss mice were subjected to 8 weeks of endurance training and mated with untrained females.

Key Findings: Trained fathers displayed typical endurance training-induced adaptations.