Publications by authors named "C Zompola"
Article Synopsis
- - The study aimed to compare levels of cerebrospinal fluid (CSF) and plasma biomarkers associated with Cerebral Amyloid Angiopathy (CAA) against healthy controls and Alzheimer’s Disease patients.
- - A meta-analysis of nine cohorts revealed significant differences in CSF levels of β-amyloids and tau proteins, with CAA patients showing lower Aβ42 and Aβ40 levels compared to healthy controls and distinct tau levels compared to both groups.
- - The findings suggest that specific biomarker profiles in CSF could help differentiate CAA from Alzheimer's and healthy individuals, while plasma biomarker levels did not show significant differences.
The management of blood pressure variability (BPV) in acute stroke presents a complex challenge with profound implications for patient outcomes. This narrative review examines the role of BPV across various stages of acute stroke care, highlighting its impact on treatment strategies and prognostic considerations. In the prehospital setting, while guidelines lack specific recommendations for BP management, emerging evidence suggests a potential link between BPV and outcomes.
View Article and Find Full Text PDFNeuropsychological profiles comparison between Multiple Sclerosis patients and Multiple Sclerosis patients with overlapping features of Systemic Lupus Erythematosus.
J Neuroimmunol
February 2024
Aim: Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE) are autoimmune disorders that may lead to cognitive impairment. This study aimed to compare the neuropsychological profiles of patients with MS, and MS and coexisting SLE features.
Methods: We included a total of 90 participants, divided into 3 groups: 30 patients with clinically definite relapsing remitting MS, 30 with coexisting MS and incomplete SLE (overlap group) and 30 healthy controls (HC).
Background: Atrial fibrillation (AF) is a frequent underlying cause of cryptogenic stroke (CS) and its detection can be increased using implantable cardiac monitoring (ICM). We sought to evaluate different risk scores and assess their diagnostic ability in identifying patients with CS with underlying AF on ICM.
Methods: Patients with CS, being admitted to a single tertiary stroke center between 2017 and 2022 and receiving ICM, were prospectively evaluated.
Introduction: Peripheral nervous system is early involved in Fabry disease (FD) and preferentially the small nerve fibers, causing the characteristic neuropathic pain crises usually beginning in childhood. Early detection of this likely underdiagnosed disease is an important approach because causal therapies are available.
Methods: We conducted a case-series study to investigate the small nerve fiber involvement in FD and its contribution to the diagnosis of the disease but also to the timely effective therapy administration.