Vegetation Fire Emissions Exacerbate Glacier Melting on the Third Pole.

Vegetation fires release a large fraction of light-absorbing components, which can contribute to the melting of snowpack and alpine glaciers. However, the relationship between variability in fire emissions and alpine glacier melting on the Third Pole (TP) remains poorly understood. This study provides evidence that carbon emissions from windward vegetation fires play a crucial role in comprehending glacier melting on the TP, particularly during the months of intense vegetation fires from March to May for monsoon-dominated glaciers and from June to October for westerlies-dominated glaciers.

Chitosan- and sodium alginate-coated dendritic mesoporous organosilica nanoparticles improve pesticide adhesion on leaves and enable dual-stimulus-responsive release.

During the application of most conventional pesticides, a significant proportion is lost through rain wash-off and leaf rolling, leading to reduced actual utilization efficiency. In this paper, aminated dendritic mesoporous organosilicon nanoparticles (DMONs-NH) were synthesized via a one-pot method and used as carriers. Carbendazim (CBZ) was then encapsulated within DMONs-NH through hydrogen bonding and electrostatic interactions.

Global vaccine research and application hotspots and trends: a systematic bibliometric analysis based on SCIE highly cited papers.

Objectives: COVID-19, a public health emergency affecting the world in 2019, not only greatly promoted the development and application of vaccines but also effectively shortened the publishing time of scientific papers. In view of these facts, the current situation, status, problems and development trends of vaccine research and application were explored through bibliometric analysis of highly cited papers in the vaccine field within the time frame of 2014-2024, and the countries, institutions, authors, funding agencies and other relevant information that contributed most to vaccine research and application were summarised.

Design: Bibliometric analysis through data analysis and visual mapping.

Cost-effectiveness analysis of durvalumab with chemotherapy and maintenance durvalumab with or without olaparib for advanced endometrial cancer.

This study evaluates the cost-effectiveness of adding durvalumab to chemotherapy, with subsequent maintenance either with olaparib (DOCT) or without olaparib (DCT), versus chemotherapy alone (CT) as a first-line treatment for advanced endometrial cancer (EC) in the United States, stratified by mismatch repair deficiency (dMMR) and proficiency (pMMR). A Markov model based on DUO-E Phase III trial data simulated disease progression and outcomes. Total costs, quality-adjusted life years (QALYs), and incremental cost-effectiveness ratios (ICER) were evaluated.

Review on application of silk fibroin hydrogels in the management of wound healing.

Wounds are regarded as disruptions in the integrity of human skin tissues, and the process of wound healing is often characterized as protracted and complex, primarily due to the potential infection or inflammation caused by microorganisms. The quest for innovative solutions that accelerate wound healing while prioritizing patient safety and comfort has emerged as a focal point. Within this pursuit, silkworm silk fibroin-a natural polymer extracted from silk cocoons-exhibits a distinctive combination of properties including biocompatibility, biodegradability, superior mechanical strength, water absorption, and low immunogenicity, which align closely with the demands of contemporary wound care.