Publications by authors named "C Z Gu"

Background: The global aging population and rapid development of digital technology have made health management among older adults an urgent public health issue. The complexity of online health information often leads to psychological challenges, such as cyberchondria, exacerbating health information avoidance behaviors. These behaviors hinder effective health management; yet, little research examines their mechanisms or intervention strategies.

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Background: Alzheimer's disease (AD) is an irreversible age-related neurodegenerative condition characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles. Di Huang Yi Zhi (DHYZ) formula, a traditional Chinese herbal compound comprising several prescriptions, demonstrates properties that improve cognitive abilities in clinical. Nonetheless, its molecular mechanisms on treating AD through improving neuron cells mitochondria function have not been deeply investigated.

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Background: Lung cancer (LC) is the leading cause of cancer-related death in humans. tRNA-derived small RNA (tsRNA) is a novel biomarker that plays a crucial role in the genesis and development of LC. In this study, we aimed to investigate the value of differentially expressed tsRNAs in LC through meta-analysis.

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Objectives: Mild Traumatic Brain Injury (mTBI) is quite prevalent in the elderly population, and the authors performed a retrospective analysis regarding the predictive value of frailty assessing tools regarding the prognosis of elderly mTBI patients.

Methods: All the patients underwent assessment of frailty upon admission using five tools including Frailty Phenotype (FP), FRAIL Scale (FS), Edmonton Frailty Scale (EFS), Groningen Frailty Indicator (GFI), and Clinical Frailty Scale (CFS). The predicting potential of tools was analyzed against the prognosis defined by the extended Glasgow Outcome Scale (GOSE).

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Purpose: To explore whether screen time moderates the relationship between family functioning and negative emotions in Chinese children with cancer.

Methods: Between November 2023 and May 2024, 206 children with cancer were recruited from a pediatric oncology ward at a tertiary hospital. Negative emotions, family functioning, and screen time were assessed using the Depression Anxiety Stress Scale-21, Family Adaptability and Cohesion Evaluation Scales, Second Edition, Chinese Version, and Screen Time Questionnaire, respectively.

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