Does music counteract mental fatigue? A systematic review.

Introduction: Mental fatigue, a psychobiological state induced by prolonged and sustained cognitive tasks, impairs both cognitive and physical performance. Several studies have investigated strategies to counteract mental fatigue. However, potential health risks and contextual restrictions often limit these strategies, which hinder their practical application.

Integrating Chemoselective Labeling and Laser-Cleavable Mass Tagging for Determination of Sialic Acids in Glycoconjugates.

Sialic acids are the terminal units of glycans in glycoproteins or glycolipids. The determination of sialic acids in glycoconjugates is crucial since they regulate essential biological functions and have a significant nutritional value. To achieve a specific and high-throughput in situ determination of sialic acids in glycoconjugates, a laser-desorption/ionization mass spectrometry (LDI-MS)-based strategy is reported by integrating chemoselective labeling and laser-cleavable mass tagging.

Positive feedback between arginine methylation of YAP and methionine transporter SLC43A2 drives anticancer drug resistance.

Yes-associated protein (YAP) activation confers resistance to chemotherapy and targeted therapy. Methionine participates in cellular processes by converting to methyl donor for the methylation of DNA, RNA and protein. However, it remains unclear whether methionine affects drug resistance by influencing YAP activity.

A filter inspired by deep-sea glass sponges for oil cleanup under turbulent flow.

Oil spill disasters lead to widespread and long-lasting social, economical, environmental and ecological impacts. Technical challenges remain for conventional static adsorption due to hydrodynamic instability under complex water-flow conditions, which results in low oil-capture efficiency, time delay and oil escape. To address this issue, we design a vortex-anchored filter inspired by the anatomy of deep-sea glass sponges (E.

SIRT7 Promotes Alcohol Associated Liver Injury via Modulating Myeloid Cell CCL2 Secretion through NF-κB Signaling Pathway.

The pathogenesis of Alcohol-associated liver disease (ALD) is complex, involving ethanol-induced enhancement of gut permeability results in the release of bacterial products from the intestine. This triggers intrahepatic inflammation and liver damage, with hepatic macrophages playing key roles in the inflammatory response to alcohol. SIRT7 a NAD-dependent type III histone deacetylase, is being recognized as a potential therapeutic target in various human diseases including cancer.