Publications by authors named "C Z Barreiro"
Objective: To evaluate the midterm survival, clinical, and hemodynamic outcomes of the On-X mechanical mitral valve, based on the 5-year results of the Prospective Randomized On-X Anticoagulation Clinical Trial (PROACT).
Method: PROACT Mitral was a multicenter study evaluating 401 patients who underwent mitral valve replacement (MVR) with either Standard or Conform-X On-X mitral valves, comparing low-dose and standard-dose warfarin. Here we report prespecified secondary outcomes of survival, New York Heart Association (NYHA) functional classification, and valve hemodynamics as assessed by core lab-adjudicated echocardiography at 1, 3, and 5 years in the pooled population.
Impact of universal use of the McGrath videolaryngoscope as the first option for all intubations in the operating room: The multicentre prospective before-after VIDEOLAR-SURGERY study protocol.
Rev Esp Anestesiol Reanim (Engl Ed)
January 2025
Article Synopsis
- The study aims to determine if the McGrath video laryngoscope, used as the first option for tracheal intubation, improves ease of intubation and reduces complications compared to the traditional Macintosh laryngoscope.
- It's conducted as a multicenter trial involving 35 anesthesiologists across several hospitals, tracking outcomes before and after implementation of the video laryngoscope.
- The study has ethical approval, requires informed consent from participants, and intends to publish its findings in a peer-reviewed journal and present at scientific conferences.
Almost one century after the Sir Alexander Fleming's fortuitous discovery of penicillin and the identification of the fungal producer as Penicillium notatum, later Penicillium chrysogenum (currently reidentified as Penicillium rubens), the molecular mechanisms behind the massive production of penicillin titers by industrial strains could be considered almost fully characterized. However, this filamentous fungus is not only circumscribed to penicillin, and instead, it seems to be full of surprises, thereby producing important metabolites and providing expanded biotechnological applications. This review, in addition to summarizing the classical role of P.
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- - Strain U can utilize biogenic amines like putrescine and cadaverine, along with their breakdown products (ɣ-aminobutyrate and δ-aminovalerate), as its only carbon sources.
- - Several gene paralogs have been identified in strain U that are responsible for catabolizing these compounds, including those encoding putrescine-pyruvate and ɣ-aminobutyrate aminotransferases.
- - Gene expression levels vary significantly based on the carbon source; putrescine upregulates certain genes while cadaverine triggers others, highlighting distinct mechanisms for polyamine metabolism in strain U.
Sulfur oxidation stands as a pivotal process within the Earth's sulfur cycle, in which species emerge as skillful sulfur-oxidizing bacteria. They are able to efficiently oxidize several reduced inorganic sulfur compounds (RISCs) under extreme conditions for their autotrophic growth. This unique characteristic has made these bacteria a useful tool in bioleaching and biological desulfurization applications.
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