Publications by authors named "C Yuh"
Objective: Dentists encounter unique occupational challenges, including stress, depression, and anxiety, that can impact their mental well-being. Therefore, it is essential to identify dentists' mental health statuses and the factors influencing them. Understanding the heterogeneity in dentists' mental health is crucial for tailored interventions.
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- Lumbar degenerative spondylolisthesis (LDS) is a condition involving spinal instability due to intervertebral disc degeneration and facet joint changes, leading to pain and potential surgery, but its causes are not well understood.
- This study examined the relationship between gut microbiome dysbiosis (an imbalance of gut bacteria) and spine health in symptomatic patients with and without LDS by analyzing fecal samples.
- Findings indicated that patients with LDS showed more severe disc degeneration, distinct gut microbiome structures, and a higher ratio of pro-inflammatory bacteria compared to those without LDS, suggesting a possible link between gut health and spinal conditions.
Background: Primary hyperparathyroidism, while increasing the susceptibility to osteoporosis, also amplifies the potential for fractures in vulnerable areas such as the femoral neck. It can also serve as an infrequent etiological factor behind vertebral compression fractures.
Case Report: This report discusses a case of multiple acute non-traumatic vertebral compression fractures in a patient diagnosed with primary hyperparathyroidism.
In silico clinical trials, particularly when augmented with artificial intelligence methods, represent an innovative approach with much to offer, particularly in the musculoskeletal field. They are a cost-effective, efficient, and ethical means of evaluating treatments and interventions by supplementing and/or augmenting traditional randomized controlled trials (RCTs). While they are not a panacea and should not replace traditional RCTs, their integration into the research process promises to accelerate medical advancements and improve patient outcomes.
View Article and Find Full Text PDFLamin A/C gene (LMNA) mutations contribute to severe striated muscle laminopathies, affecting cardiac and skeletal muscles, with limited treatment options. In this study, we delve into the investigations of five distinct LMNA mutations, including three novel variants and two pathogenic variants identified in patients with muscular laminopathy. Our approach employs zebrafish models to comprehensively study these variants.
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