Publications by authors named "C Yalcinkaya"
Cerebral cortex development in humans is a highly complex and orchestrated process that is under tight genetic regulation. Rare mutations that alter gene expression or function can disrupt the structure of the cerebral cortex, resulting in a range of neurological conditions. Lissencephaly ('smooth brain') spectrum disorders comprise a group of rare, genetically heterogeneous congenital brain malformations commonly associated with epilepsy and intellectual disability.
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- The study aimed to compare serum Metrnl levels in pregnant women with gestational diabetes mellitus (GDM) to those without it, involving a total of 180 participants.
- Results showed that women with GDM had significantly lower median serum Metrnl levels (1.16 ng/mL) compared to healthy controls (2.2 ng/mL).
- The study concluded that decreased serum Metrnl levels in GDM patients could indicate a potential biomarker for the condition, although the reasons for this decrease are still unknown and require further research.
Investigation of serum spexin concentrations in pregnant women diagnosed with hyperemesis gravidarum.
J Matern Fetal Neonatal Med
December 2024
Article Synopsis
- The study aimed to examine serum levels of spexin in pregnant women with hyperemesis gravidarum (HG), a condition characterized by severe nausea and vomiting during pregnancy.
- Conducted at a hospital in Turkey, the research involved 80 pregnant women, comparing 40 diagnosed with HG to 40 healthy controls.
- Results showed that women with HG had significantly higher serum spexin levels (342.4 pg/ml) compared to the control group (272.8 pg/ml), suggesting a potential link between spexin and HG symptoms that warrants further investigation.
Purpose: In mucinous ovarian tumors, preoperative prediction of histological subgroup is important for treatment approach. Therefore, we aimed to determine salient magnetic resonance imaging (MRI) findings and estimate optimal cut off values for quantitative features in differential diagnosis of benign, borderline and malignant mucinous ovarian tumors.
Methods: Between January 2011 and December 2021, preoperative MRI scans of 50 patients with mucinous ovarian tumors (n = 54) were evaluated retrospectively.
Objective: Preeclampsia, whose pathophysiology is still not fully elucidated today, is a pregnancy-specific disease that affects most organ systems in pregnant women, including the central nervous system. In this context, we aimed to investigate the effects of preeclampsia on blood flow in the ophthalmic artery of the eye, which is considered a part of the central nervous system.
Materials And Methods: This prospective, non-interventional cohort study was conducted between February 2022 and June 2022 at Umraniye Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.