Diffuse expression of p16 in pancreatic neuroendocrine tumors (PanNETs) and the association of morphology variants.

Objective: Distinguishing grade 3 pancreatic neuroendocrine tumors (PanNETs) from neuroendocrine carcinomas (PanNECs) is sometimes challenging. Recently, a diffuse p16-positive pattern was reported in PanNECs but not in grade 3 PanNETs, suggesting that p16 could help differentiate these entities. This study aimed to investigate p16 expression in PanNETs of various grades and its association with clinicopathologic features.

The Effect of Cyber-Ostracism on Social Anxiety Among Undergraduates: The Mediating Effects of Rejection Sensitivity and Rumination.

In order to examine the relationship between cyber-ostracism and social anxiety among undergraduates, as well as to investigate the mechanisms underlying the effects of cyber-ostracism, rejection sensitivity, and rumination on social anxiety, this study recruited 864 undergraduate students from Jiangsu and Guangdong Provinces in China using a cluster sampling method. The participants completed the Cyber-Ostracism Questionnaire, the Chinese version of the Interaction Anxiousness Scale, the Chinese version of the Rejection Sensitivity Questionnaire, and the Chinese version of the Ruminative Responses Scale. Furthermore, the mediating effects were examined using the structural equation modeling (SEM) method.

[Comparison of short-term clinical efficacy between CO external fixation and internal fixation with steel plate in the treatment of unstable distal radius fractures].

Objective: To evaluate the short-term clinical efficacy of external fixation and internal fixation with steel plate in the treatment of unstable distal radius fractures (AO-23C type), based on the principles of Chinese osteosynthesis (CO).

Methods: Forty-eight patients with unstable distal radius fractures between January 2022 and February 2023 were retrospectively analyzed and divided into the CO external fixation group and internal fixation group. CO external fixation group consisted of 25 patients, including 7 males and 18 females, aged from 37 to 56 years old with an average of ( 52.

Efficacy and application potential of purified hydrocolloid coatings sprayed onto maize seeds subjected to anti-aging.

The use of purified hydrocolloids extracted from waste-activated sludge has significant potential for preventing seed deterioration caused by aging. In this study, we compared the advantages and disadvantages of 3 types of purified hydrocolloid seed coatings from different waste sludges and one commercial seed coating at different spraying times (2, 4, 6, and 8). Compared with coated maize seeds, uncoated maize seeds underwent significant functional changes during the aging process according to the infrared spectroscopy results.