Comparison of Rifaximin Monotherapy and Rifaximin Combined with Probiotics in Patients with Irritable Bowel Syndrome: A Randomized Controlled Trial.

: Rifaximin is a nonabsorbable antibiotic used to treat irritable bowel syndrome (IBS). Recent studies on eradication treatment have reported synergistic effects and low adverse effects when antibiotics are used in combination with probiotics; yet, such studies have not been conducted in IBS. Probiotics can enhance gut microbiota modulation, inhibition of pathogen adhesion to the gut epithelia, improvement in gut barrier function, anti-inflammatory effects, and improvement of gut immunity.

Corrigendum to "Ginsenoside-Re-rich ethanol extract of Panax ginseng berry enhances healthspan extension via mitostasis and NAD metabolism" [J Ginseng Res Volume 49, Issue 1, January 2025, Pages 92-102].

[This corrects the article DOI: 10.1016/j.jgr.

Prevalence of Airflow Limitation and Emphysema in Lung Cancer Screening Populations: A Systematic Review and Meta-analysis.

Background: Early detection and treatment of chronic obstructive pulmonary disease (COPD) are becoming important for improving the prognosis of individuals who smoke heavily. Despite the higher risk of COPD among individuals participating in lung cancer screening, many of these patients remain underdiagnosed.

Research Questions: How many participants in lung cancer screening have emphysema or airflow limitation? If spirometry is incorporated into the screening, how many additional patients with airflow limitation could be newly identified?

Study Design And Methods: The Ovid-MEDLINE and Embase databases were searched from inception to November 30, 2023.

RPS24 haploinsufficiency impairs erythropoiesis in the Diamond-Blackfan anemia zebrafish model via the STAT6-SATB1 pathway.

Diamond-Blackfan anemia (DBA) is a rare bone marrow failure disorder primarily caused by mutations in ribosomal proteins (RPs), including RPS24, leading to impaired erythropoiesis. Despite advances in our understanding of the roles of other RPs, the mechanisms underlying RPS24-related DBA remain unclear. Therefore, in this study, we aimed to investigate the effect of RPS24 haploinsufficiency on erythropoiesis using a zebrafish model.