Publications by authors named "C Y Maximilian Png"
Introduction: Despite the many benefits of smartphones, researchers have raised concerns over problematic smartphone use (PSU) and its negative effects on physical and psychological well-being. Studies examining PSU and its impact among adults remain limited. Hence, we aim to examine the prevalence of PSU among adults in Singapore, and explore its associations with smartphone activities, sleep quality, and psychological well-being, as well as age and gender-related differences in these associations.
View Article and Find Full Text PDFIn this study, we construct Fabry-Perot cavities in which nanostructured, thin resonant metasurfaces act as mirrors. We develop a temporal coupled-mode theory and provide an accurate description of the resonances supported by these cavities, deriving analytically their transmission characteristics. The presence of metasurface mirrors introduces a substantial group delay, causing the field concentration to shift from the bulk of the cavity towards the regions close to the two metasurfaces.
View Article and Find Full Text PDFNotch1 plays various roles in cancer development, and Notch1-induced transactivation is controlled by phosphorylation of its cleaved intracellular domain. However, it is unclear whether there are phosphatases capable of dephosphorylating the cleaved Notch1 transmembrane/intracellular region (NTM) to regulate its function. Here, we show that DUSP6 can function as a phosphatase for Notch1, thereby regulating NTM stability and transcriptional activity, thus influencing colorectal cancer (CRC) development.
View Article and Find Full Text PDFArticle Synopsis
- Common cold coronaviruses (ccCoVs) and influenza viruses are common causes of upper respiratory infections, but the health effects of ccCoV infections are not well understood.
- A study involving 3,935 outpatients compared symptoms and outcomes between ccCoV and influenza infections, finding that sore throat, nasal discharge, headache, and myalgia were more common in ccCoV, while fever was prevalent in influenza cases.
- Patients with underlying health conditions had increased primary care visits for respiratory symptoms following both infections, suggesting that managing these comorbidities is crucial to reduce negative health impacts.
Designing a Perioperative Mind-Body Intervention for Peripheral Vascular Interventions.
Glob Adv Integr Med Health
September 2024
Background: Peripheral vascular interventions (PVIs) performed under procedural sedation and analgesia (PSA) can be associated with anxiety and poor compliance with patient instructions during surgery. Mind-body interventions (MBIs) such as meditation have demonstrated the potential to decrease perioperative anxiety, though this area is understudied, and no tailored interventions have been developed for the vascular surgical patient population.
Objectives: We aimed to design a perioperative MBI that specifically targeted vascular surgical patients undergoing PVIs under PSA.