[Prenatal diagnosis of fetal chromosomal aneuploidies using quantitative fluorescent PCR (QF-PCR)].

The trisomy of the 21 chromosomes is one of the most important chromosomal anomalies and is responsible for Down syndrome. It persists in Poland in 1/700 birth. The risk of childbirth with Down syndrome grows with age, especially in women after 35 years old.

Synthesis and biological properties of new chimeric galanin analogue GAL(1-13)-[Ala10,11]ET-1(6-21)-NH2.

Several chimeric peptides consisting of the N-terminal fragment of galanin (GAL) and C-terminal fragments of other bioactive peptides (e.g. substance P, bradykinin, neuropeptide Y, mastoparan) have been synthesized and reported as high-affinity galanin receptor antagonists.

[Risk of diabetes mellitus after pregnancy complicated by gestational diabetes mellitus (GDM)].

Objectives: The aim of the study was an assessment of glucose tolerance disorders' (GTD) prevalence after pregnancy complicated by GDM.

Design: Retro- and prospective clinical study.

Material And Methods: The group of 461 women having GDM in their index pregnancies was invited to postpartum glucose metabolism assessment.

HPV and histological status of pelvic lymph node metastases in cervical cancer: a prospective study.

Aims: The purpose of this prospective study was to describe the incidence and distribution pattern of human papillomavirus (HPV) DNA in intraoperative dissected lymph nodes and to relate this to the pathological confirmation of metastasis.

Methods: Samples of primary cervical cancer lesions and dissected lymph nodes were obtained from women undergoing surgical treatment. The presence of HPV DNA was detected by the polymerase chain reaction.

[Quantity estimation of the E2/E6 HPV gene products ratio can be a prognostic marker for the stage of the cervical cancer carcinogenesis].

Unlabelled: Cervical cancerogenesis is presently considered to be connected with human papillomavirus (HPV) infection of cervical epithelial cells. Genomic integration of an HPV DNA into epithelial cells is a probable factor increasing cervical carcinoma incidence.

The Aim: Of the study was to evaluate the calculated ratios of HPV 16 gene amplification products with multiplex PCR.