Publications by authors named "C Wilbert"
Introduction: Stroke is a major cause of morbidity and mortality worldwide. While electroencephalography (EEG) offers valuable data on post-stroke brain activity, qualitative EEG assessments may be misinterpreted. Therefore, we examined the potential of quantitative EEG (qEEG) to identify key band frequencies that could serve as potential electrophysiological biomarkers in stroke patients.
View Article and Find Full Text PDFPoint-of-care ultrasound has become an integral part of the evaluation of monocular vision loss. Most commonly, it has been used to evaluate retinal detachment, vitreous hemorrhage, and posterior vitreous detachment. Point-of-care ultrasound can also be used to evaluate central retinal arterial occlusion, whereby a retrobulbar spot sign is present.
View Article and Find Full Text PDFThe direct conversion of a hydroxamic acid to an amine has been accomplished in a single step in the synthesis of HIV drug candidate BMS-955176. This process utilizes catalytic base and proceeds under mild conditions (CHCN, cat. DBU, 60 °C), without the need for strong electrophiles required for typical Lossen rearrangements, and can be applied to aliphatic and aromatic hydroxamic acids.
View Article and Find Full Text PDFArticle Synopsis
- Advances in critical care are changing death patterns in trauma patients, prompting a study on mortality rates of those who survive their initial hospitalization.
- A retrospective analysis of a Level-1 trauma center showed that, out of 1,695 critically injured patients, 67% were discharged alive, with 86% of those still alive two years later; however, nearly half of those who died did so within the first year post-discharge.
- Factors such as longer hospital and ICU stays, the need for specific medical procedures, and demographic variables like age and gender were linked to higher mortality rates, suggesting that patients with extended ICU stays may need more thorough post-discharge care discussions.