Volumetric dried blood spots for determination of phosphatidylethanol: Validation of a liquid chromatography tandem masspectrometry method and clinical application.

Phosphatidylethanol (PEth) measurement in whole blood samples is established as a specific alcohol biomarker with clinical and forensic applications. Establishment of dried blood spots (DBSs) as a specimen for PEth determination offers several advantages and was the focus of this work. A liquid chromatography tandem mass spectrometry method using a 96-well format for sample preparation was developed and validated.

Impact of an Okinawa/Nordic based diet on endocrinological and periodontal conditions in individuals with type 2 diabetes. A randomized case-control study.

Objectives: To assess if the results following intake of a diet using an Okinawan-based Nordic diet (OBND) over one month differs in endocrinological, periodontal clinical outcome, and serum cytokine levels compared to a standard hospital care diet in individuals with diabetes type 2 (T2D) (control group).

Background: Scientific evidence suggests that the use of diet for individuals with T2D may be beneficial.

Methods: Participating individuals with T2D were randomly assigned to a test (OBND) (n = 14), or control group (n = 16).

Periodontal conditions, retinopathy, and serum markers in individuals with type 1 diabetes.

Background: The prevalence of diabetes is high and increasing. Periodontitis has been identified as a risk factor in both type 1 and 2 diabetes. The study purpose was to assess periodontal conditions, retinopathy, and serum glutamic acid decarboxylase antibody (GADA) titers in relation to retinopathy in individuals with type 1 diabetes (T1D).

Water and ethanol extracts of leaves show anti-inflammatory activity on oral epithelial cells.

Context: The leaves of have been used for the treatment of wounds and inflammation in folk medicine from prehistoric times. However there is no report on the use of to treat inflammation in oral epithelial cell lines.

Objective: The present study was undertaken to reveal possible anti-inflammatory effects of leaf extracts on oral epithelial cells

Materials And Methods: Water- and ethanol-based extracts of leaves were prepared from freeze-dried plant material, and tested using the oral epithelial cell line H400.

Improved General and Oral Health in Diabetic Patients by an Okinawan-Based Nordic Diet: A Pilot Study.

Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND).