Publications by authors named "C Wester"

Introduction: Antiretroviral therapy (ART) increases the life expectancy of persons living with HIV (PLWH), but not without potentially serious adverse effects. Tenofovir disoproxil fumarate (TDF) can cause nephrotoxicity, manifesting as acute kidney injury (AKI) that may persist after treatment discontinuation. Kidney injury biomarkers such as kidney injury molecule-1 (KIM-1), retinol-binding protein-4 (RBP-4), interleukin-18 (IL-18), and neutrophil gelatinase-associated lipocalin (NGAL) can aid early diagnosis and predict TDF-associated nephrotoxicity.

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Objectives: The growing care demands of an aging population and a smaller workforce is a big societal problem. Therefore, knowledge on how to organize eldercare work without hampering workers` health is needed. We aimed to investigate if workers` daily number of residents cared for over 14 months is associated with low-back pain in eldercare workers.

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Background And Objective: Sexual health research among women living with human immunodeficiency virus (HIV) has focused mainly on sexual practices and risk behaviors, with little consideration for treating sexual dysfunction and improving sexual satisfaction. The aim of this pilot study was to assess the effectiveness of an adaptive counseling care model in the management of female sexual dysfunction (FSD) among women living with HIV and without HIV in northern Nigeria.

Methods: This was a prospective cohort study of 200 women with HIV and a matched comparison arm of 200 women without HIV.

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Article Synopsis
  • Severe acute symptomatic hypocalcemia is a serious health issue often presenting as painful spasms, and innovative methods like metabolomics and genetic profiling may help identify those at risk and guide treatments.
  • The study aimed to determine the prevalence of hypocalcemia in urban Kano by analyzing retrospective data from hospital patients in 2023, finding a prevalence rate of 52.2%, with females being more affected than males.
  • Results highlight the urgent need for improved understanding of hypocalcemia's genetic factors and the potential for developing targeted public health initiatives for high-risk populations.
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Article Synopsis
  • - This study focuses on the increased risk of cardiovascular diseases, specifically right ventricular (RV) dysfunction, in people living with HIV (PLWH) in northwest Nigeria, emphasizing the need for more research in low- and middle-income settings.
  • - Researchers conducted a retrospective analysis of 330 adults, including HIV-positive individuals and age- and sex-matched HIV-negative controls, using advanced imaging techniques to evaluate heart function.
  • - Results indicated that 14.5% of HIV-positive participants showed signs of RV dysfunction, linked to factors like age and left ventricular ejection fraction, while no HIV-negative participants exhibited such dysfunction.
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