Publications by authors named "C Warner Hoornenborg"
Article Synopsis
- The study investigated how different diets (low-fat vs. high-fat/sucrose) affected weight loss after Roux-en-Y gastric bypass (RYGB) surgery in rats.
- Rats fed a high-fat/sucrose diet lost more weight post-surgery compared to those on a low-fat diet, primarily due to lower energy intake and initial body weight differences.
- Interestingly, continuing the high-fat/sucrose diet did not hinder recovery from surgery, even though low-fat dieting led to signs of malaise following RYGB.
The sub-diaphragmatic vagus innervates various organs involved in the control of glucose homeostasis including the liver, pancreas and the intestines. In the current study, we investigated the effect of acute electrical stimulation of the anterior trunk of the sub-diaphragmatic vagus on glucose fluxes in anaesthetized adult male rats. After overnight fast, rats underwent either vagus nerve stimulation (VNS+, n = 11; rectangular pulses at 5 Hz, 1.
View Article and Find Full Text PDFPurpose: Ileal transposition (IT) allows exploration of hindgut effects of bariatric procedures in inducing weight loss and reducing adiposity. Here we investigated the role of dietary macronutrient content on IT effects in rats.
Methods: Male Lewis rats consuming one of three isocaloric liquid diets enriched with fat (HF), carbohydrates (HC), or protein (HP) underwent IT or sham surgery.
Background: Ileal Transposition (IT) was developed as a model to study body weight reduction without the restrictive or malabsorptive aspects of other bariatric surgeries, but the exact mechanisms of the alterations in body weight after IT are not completely understood.
Objective: To provide a detailed description of the surgical procedure of IT, and describe its effect on energy balance parameters.
Methods: Adult male Lewis rats underwent either IT (IT+) or sham (IT-) surgery.