Publications by authors named "C Walcott"

Article Synopsis
  • The article DOI: 10.3389/fimmu.2021.641188 has been identified as needing corrections.
  • These corrections aim to address inaccuracies or clarify points within the original publication.
  • Readers are encouraged to refer to the updated version for the most accurate information.
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Article Synopsis
  • Lymphocyte migration is essential for immune surveillance and requires precise regulation by chemokines and their receptors.
  • Protein geranylgeranylation, a post-translational modification, is vital for proper signaling of chemokine receptors and influences T cell movement and function.
  • Deficiency in protein geranylgeranylation hampers thymocyte egress, affects T cell homing, alters T helper cell differentiation, and provides resistance to autoimmune conditions in specific mouse models.
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In the early 1970s, Floriano Papi and colleagues proposed the olfactory-navigation hypothesis, which explains the homing ability of pigeons by the existence of an odor-based map acquired through learning. This notion, although supported by some observations, has also generated considerable controversy since its inception. As an alternative, Paulo Jorge and colleagues formulated in 2009 the olfactory-activation hypothesis, which states that atmospheric odorants do not provide navigational information but, instead, activate a non-olfactory path integration system.

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Sickle cell trait (SCT) places individuals at risk of passing an abnormal hemoglobin gene to biological children and is associated with rare but serious complications. The present study sought to examine knowledge of SCT and awareness of personal trait status among 258 young African American adults. Participants were surveyed regarding demographics, medical history, and sources of sickle cell information before completing a trait knowledge questionnaire.

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Background: The aims of this study were to describe guardian perceptions of the experiences of a sample of youth with sickle cell disease (SCD) in rural emergency departments (EDs) with a focus on overall patient satisfaction and characteristics of care.

Procedure: Guardians of 139 children with SCD (0 to 17 y) seen at a rural pediatric SCD clinic completed a survey concerning their children's ED experiences in the past 6 months, including information about ED wait times, quality of communications and interactions with the ED health care providers, pain management, perceptions of speed of care, and overall satisfaction.

Results: About 41% of guardians reported that their child visited the ED in the past 6 months.

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