Characterization of human placental fetal vessels in gestational diabetes mellitus.

Gestational diabetes mellitus is one of the most common complications during pregnancy. Its prevalence is rapidly increasing worldwide. Gestational diabetes mellitus is leading to an elevated risk for the development of endothelial dysfunction and cardiovascular diseases both in the mother and the child in later life.

Pursuing unprecedented anisotropic morphologies of halide-free Pd nanoparticles by tuning their nucleation and growth.

In this paper, a highly effective and scalable polyol-based modified procedure is reported, yielding shape-controlled Pd nanoparticles (NPs) formed two distinct growth mechanisms as a function of apparent pH. Starting from tetraethylammonium tetrahydroxypalladate (TEA)[Pd(OH)], a halide-free precursor, the resulting shape of the NPs ranged from highly defective worm-like nanostructures to well-defined polyhedra (tetrahedra, octahedra and 5-fold twins) as shown by TEM, HRTEM, and STEM. The effect of the different synthesis parameters was thoroughly investigated, finding that apparent pH - modulated by adding diluted HNO - is the key parameter in determining the final size and shape of Pd NPs, whose evolution was followed during the reaction.

Heat-induced aggregation kinetics of potato protein - Investigated by chromatography, calorimetry, and light scattering.

In this study, the heat-induced aggregation behavior of patatin rich potato protein isolate (PPI) was investigated by reversed-phase high-pressure liquid chromatography (RP-HPLC), differential scanning calorimetry (DSC), and dynamic light scattering. It could be shown that aggregation already occurs at low temperatures, despite low degrees of unfolding. The unfolding temperature, determined by DSC, coincided with a change in the reaction kinetics, which is determined by the unfolding step below a critical temperature up to the point, where the proteins are completely unfolded.

Alteration of Intestinal Microbiome of Infected Hamsters during the Treatment with Specific Cow Antibodies.

infection (CDI) often develops after pretreatment with antibiotics, which can lead to damage of the intestinal microbiome. The approach of this study was to use specific polyclonal antibodies isolated from the milk of immunized cows to treat CDI, in contrast to the standard application of nonspecific antibiotics. To gain a deeper understanding of the role of the microbiome in the treatment of CDI with bovine antibodies, stool and intestinal fluid samples of hamsters were collected in large quantities from various treatments (>400 samples).