Publications by authors named "C W Too"
Article Synopsis
- Advanced ultrasound techniques offer better insights into non-melanoma skin cancers compared to traditional methods like dermoscopy, enhancing assessment of tumor margins and morphology.
- In a study of 11 skin tumors (mostly basal and squamous cell carcinomas) from patients aged 66 to 98, ultrasound effectively measured tumor depth and correlated well with histological findings.
- The ultrasound showed that all tumors were solid and stiff, with high levels of neovascularity, indicating its potential as a quick and useful pre-operative tool.
Objective: Autoantibodies serve as essential clinical biomarkers and may indicate etiological mechanisms in rheumatic diseases. In light of the increasing knowledge concerning the diversity and biologic implications of anti-citrullinated peptide/protein antibodies (ACPAs), we have re-evaluated the association between the ACPA response and the HLA-DRB1 allelic groups, known to represent a major genetic risk factor for rheumatoid arthritis (RA).
Methods: We explored a collection of 4,392 well-characterized incident patients with RA of White European descent from the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) new-onset RA study, as well as 1,199 cases of patients with RA of Southeast Asian origin from the Malaysian EIRA study.
Tofacitinib is the first oral JAK inhibitor approved for treating rheumatoid arthritis (RA). To enhance our understanding of tofacitinib drug response, we used hierarchical clustering to analyse the profiles of patient who responded to the treatment in a real-world setting. Patients who commenced on tofacitinib treatment were selected from 12 major rheumatology centres in Malaysia.
View Article and Find Full Text PDF