Publications by authors named "C W Daeschner"

Thromboembolism is a well-known complication of cancer including acute myeloid leukemia (AML) especially in patients with high myeloblast counts. However, spontaneous vaso-occlusion in the main arteries is very rare especially in patients with low blast counts and no pre existing vasculopathy. We report the case of a 3-year-old male with refractory AML who developed spontaneous bilateral internal carotid artery occlusion with diffuse cerebral infarcts.

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Objective: To investigate mood as a mediator or moderator of the pain-sleep relationship in children with sickle cell disease (SCD).

Method: Children with SCD (n = 20; aged 8-12 years) completed daily diaries assessing mood, sleep, and pain for up to 2 months. Data was analyzed using multilevel modeling.

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Objective: To investigate the pain-sleep relationship in children with sickle cell disease (SCD) and the influence of stress and pain medication use on this relationship.

Method: Children with SCD (n = 20; aged 8-12 years) completed daily diaries assessing sleep, pain, stress, and pain medication use for up to 2 months. Data analyzed using multilevel modeling.

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Article Synopsis
  • - The study looked at how optimism affects pain medication use in adolescents with sickle cell disease, involving 27 participants (18 females, 9 males) who reported pain severity and medication use daily.
  • - Findings showed that adolescents with more severe pain used more analgesics and opioids, but the level of optimism influenced this relationship significantly.
  • - Specifically, optimistic adolescents matched their medication use more effectively to their pain levels, suggesting that psychosocial factors like optimism should be considered in pain management strategies.
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Objective: To determine the extent to which daily stress and mood are associated with pain, health-care use, and school activity in adolescents with sickle cell disease (SCD).

Method: Adolescents with SCD (n = 37; aged 13 to 17 years) completed daily diaries assessing pain, stress, mood, activity, and health-care use for up to 6 months. Multilevel modeling was used to analyze the data.

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