Publications by authors named "C W Canal"

Bats are mammals with high biodiversity and wide geographical range. In Brazil, three haematophagous bat species are found. is the most documented due to its role as a primary host of rabies virus in Latin America.

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The mountain context represents a suitable setting for promoting health. In view of the Olympic Games, which are expected to take place in the Dolomites area in 2026, the outdoor Alpine environment must continue to meet all the health and safety requirements. Our recent experience, implemented in this area since summer 2024 through the Prevention Department of the Local Health Authority ULSS 1 Dolomiti, aims to encourage multi-sector preventive public health policies, in order to improve the "Shelters" ("rifugi", in Italian) hygiene, to strengthen the safety requirements, and to implement preventive projects.

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Results from clinical trials show that serotonergic psychedelics have efficacy in treating psychiatric disorders, where currently approved pharmacotherapies are inadequate. Developing psychedelic medicines, however, comes with unique challenges, such as tempering heightened anxiety associated with the psychedelic experience. We conceived a new strategy to potentially mitigate psychedelic effects with defined electromagnetic signals (ES).

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Article Synopsis
  • The study investigates how age affects outcomes in patients with thoracic injuries, particularly focusing on rib fractures among geriatric patients compared to younger individuals.
  • Using data from a level I trauma center over five years, the research matched patients based on injury patterns and gender, revealing older adults had more comorbidities but fewer pulmonary complications and shorter hospital stays.
  • Results indicated that although older patients had different injury patterns and a higher mortality rate, age alone isn't the best predictor of serious outcomes; the study suggests further research using a rib fracture scoring system to identify at-risk patients.
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Mitragynine, an alkaloid present in the leaves of Mitragyna speciosa (kratom), has a complex pharmacology that includes low efficacy agonism at μ-opioid receptors (MORs). This study examined the activity of mitragynine at adrenergic α receptors (AαRs) in vitro and in vivo. Mitragynine displaced a radiolabeled AαR antagonist ([H]RX821002) from human AαRs in vitro with lower affinity (K = 1260 nM) than the agonists (-)-epinephrine (K = 263 nM) or lofexidine (K = 7.

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