Publications by authors named "C W BEARD"
Objective: The objective of this study was to evaluate the preliminary effectiveness of an electronic pill bottle with automated reminders on hydroxychloroquine (HCQ) adherence in children with pediatric systemic lupus erythematosus (pSLE).
Methods: This was a self-controlled, open label, direct-to-family pilot trial. Children with pSLE treated with HCQ were recruited from the Childhood Arthritis and Rheumatology Research Alliance Registry.
Background/objectives: The biological basis for behavioral manifestations of Alzheimer's disease remains unclear. Emotional and behavioral alterations of Alzheimer's disease can result in substantial caregiver burden and lack effective management. This study expands upon previous work investigating behavioral alterations in mice with Alzheimer's disease and a potential treatment of increasing brain-derived neurotrophic factor (BDNF) using repetitive transcranial magnetic stimulation (rTMS).
View Article and Find Full Text PDFCurrent biomechanical models suggest that butterflies and moths use their proboscis as a drinking straw pulling nectar as a continuous liquid column. Our analyses revealed an alternative mode for fluid uptake: drinking bubble trains that help defeat drag. We combined X-ray phase-contrast imaging, optical video microscopy, micro-computed tomography, phylogenetic models of evolution and fluid mechanics models of bubble-train formation to understand the biomechanics of butterfly and moth feeding.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how post-traumatic stress symptoms (PTSS) impact treatment outcomes like depression, anxiety, and overall functioning among patients in partial hospital programs (PHP).
- A total of 1,298 adults participated, with linear regression analyses showing that those with severe PTSS had poorer improvement in mental health compared to those without trauma history or less severe symptoms.
- The findings suggest that severe PTSS could predict treatment outcomes in acute psychiatric settings, highlighting the importance of trauma-informed care despite limitations in generalizability due to the study's design.