Publications by authors named "C Vluggen"
Article Synopsis
- The TB incidence rate in the Brussels-Capital Region is significantly higher (3-fold) than in the rest of Belgium, prompting ongoing genetic studies of TB strains from local patients.
- The study, which included genotyping of strains from 945 patients, identified LAM and Haarlem as the most prevalent TB lineages, with a notable presence of Beijing strains among the MDR subgroup, especially in Eastern European patients.
- Despite a high proportion of foreign-born patients (75.7%), the analysis reveals limited trans-national transmission, and overall, the epidemiological situation appears stable, emphasizing the need for funding to support ongoing TB control efforts through molecular epidemiology.
Mycobacterium avium subsp. hominissuis (Mah) represents a health concern for humans and to a lesser extent for pigs, but its zoonotic potential remains elusive. Using multispacer sequence typing (MST) we previously identified 49 different genotypes of Mah among Belgian clinical and porcine isolates, with 5 MSTs shared by both hosts.
View Article and Find Full Text PDFMycobacterium chimaera arouses an increasing public health concern, as this non-tuberculous mycobacterium (NTM) has recently been associated with life-threatening cardiac infections. M. chimaera and Mycobacteriumintracellulare are genetically very close but recently appeared to present different epidemiological and clinical significance.
View Article and Find Full Text PDFThis paper announces the genome sequences of four strains of Mycobacterium avium subsp. hominissuis, isolated from cases of lymphadenopathy in swine and humans, differing in virulence in a murine intranasal infection model.
View Article and Find Full Text PDF