Publications by authors named "C Vivas"
Background: We studied the poorly-known dynamics of circulating DNA (cir-nDNA), as monitored prospectively over an extended post-surgery period, in patients with cancer.
Methods: On patients with stage III colon cancer (N = 120), using personalised molecular tags we carried out the prospective, multicenter, blinded cohort study of the post-surgery serial analysis of cir-nDNA concentration. 74 patients were included and 357 plasma samples tested.
Article Synopsis
- Different tumors with the same diagnosis can act differently in response to treatments because they can have unique genetic features.
- Scientists studied a large number of breast cancer cases and found that certain inherited traits from parents may help explain why some tumors grow or change in different ways.
- Tumors that manage to survive the immune system's attacks are often more aggressive and less responsive to treatment, but understanding these genetic differences can help doctors target better treatments.
On page 5, 3rd paragraph, line 7, where it reads, (in red): "(...
View Article and Find Full Text PDFIn vitro cellular models provide valuable insights into the adaptive biochemical mechanisms triggered by cells to cope with the stress situation induced by hypoxia and reoxygenation cycles. The first biological data generated in studies based on this micrometric life-scale has the potential to provide us a global overview about the main biochemical phenomena presented in some reported preconditioning therapies in life-scale of higher dimensions. Thus, in this study, a cell incubator was designed and manufactured to produce a cellular model of heart hypoxia followed by reoxygenation (HfR) through consecutive repetitions of hypoxia-normoxia gas exchange.
View Article and Find Full Text PDFIntroduction: Human resources in ophthalmology have recently received particular attention, and it has been questioned whether there is a sufficient number of workers. The aim of this study was to analyze and characterize Portugal's ophthalmologist population.
Methods: In this descriptive, cross-sectional study, an online questionnaire was sent to all ophthalmologists registered with the Portuguese College of Ophthalmology in December 2021.