The efficacy of ketotifen in a controlled double-blind food challenge study in patients with food allergy.

The effectiveness of oral ketotifen was compared with that of placebo in 26 patients with food allergy in a randomized, double-blind parallel study. Patients were selected on the basis of food allergy as established by history, clinical improvement after an exclusion diet, and reappearance of the symptoms after a challenge with the food. Thirteen patients were given ketotifen and 13, placebo.

Effects of pindolol and metoprolol on plasma lipids and lipoproteins.

1 The effects of two beta-adrenoceptor blocking drugs, pindolol and metoprolol, on plasma lipids and lipoproteins were studied in sixteen hypertensive patients (WHO I-I) by a cross-over design, with two active treatment periods of 12 weeks each. 2 Neither pindolol nor metoprolol had any effect on total plasma cholesterol (total-C), triglycerides (TG) or low-density lipoprotein cholesterol (LDL-C). 3 Pindolol significantly increased high-density lipoprotein cholesterol (HDL-C).

A comparison between inhaled clenbuterol and salbutamol in chronic bronchitis with reversible airway obstruction.

Twenty-one patients with chronic bronchitis and reversible airway obstruction participated in two single-blind, cross-over, placebo-controlled studies in inhaled clenbuterol - a new bronchodilator - and salbutamol. Nine patients participated in a dose-response study. Clenbuterol 10 microgram/puff, salbutamol 100 microgram/puff and placebo, were given by pressurized aerosol in cumulative doses of 1, 2, 4, 8, and 16 inhalations of each drug and placebo.

Oral NAB 365 (clenbuterol) and terbutaline in chronic obstructive lung disease: a double-blind, two-week study.

The bronchodilator effects of large oral doses of clenbuterol (30 micrograms, t.i.d.