Publications by authors named "C Verdonk"

Article Synopsis
  • The study investigates how focused ultrasound (LIFU) can modify brain responses tied to heartbeat, known as heartbeat evoked potentials (HEP), and focuses on specific brain regions like the insula and dorsal anterior cingulate cortex (dACC).
  • Healthy participants received targeted LIFU while their brain activity (EEG) and heart activity (ECG) were monitored, with the main goal of observing changes in HEP amplitudes.
  • Results showed that LIFU to the posterior insula reduced HEP amplitudes, but it did not alter heart rate or variability, indicating the potential for targeting brain areas to influence interoceptive processing.
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The regulation of virulence in plant-pathogenic fungi has emerged as a key area of importance underlying host infections. Recent work has highlighted individual transcription factors (TFs) that serve important roles. A prominent example is PnPf2, a member of the Zn2Cys6 family of fungal TFs, which controls the expression of effectors and other virulence-associated genes in Parastagonospora nodorum during infection of wheat.

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The fungus Parastagonospora nodorum causes septoria nodorum blotch on wheat. The role of the fungal Velvet-family transcription factor VeA in P. nodorum development and virulence was investigated here.

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Background: The heartbeat evoked potential (HEP) is a brain response time-locked to the heartbeat and a potential marker of interoceptive processing. The insula and dorsal anterior cingulate cortex (dACC) are brain regions that may be involved in generating the HEP. Low-intensity focused ultrasound (LIFU) is a non-invasive neuromodulation technique that can selectively target sub-regions of the insula and dACC to better understand their contributions to the HEP.

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Article Synopsis
  • - A 16-year-old male experienced cardiogenic shock caused by malfunction of his On-X mitral valve prosthesis, which was linked to a leaflet detaching and traveling through an aortic mechanical valve.
  • - He had to have an emergency surgery to replace the malfunctioning mitral valve, followed by another procedure to remove the dislodged leaflet a few days later.
  • - After these surgical interventions, the patient made a full recovery.
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