This study aimed to evaluate the possible anticancer effects of two different pillar[5]arene derivatives (5Q-[P5] and 10Q-P[5]) on two different pancreatic cancer cell lines in vitro. For this purpose, changes in the expression of major genes that play a role in apoptosis and caspase pathways were investigated. Panc-1 and BxPC-3 cell lines were used in the study and the cytotoxic dose of pillar[5]arenes was determined by the MTT method.
View Article and Find Full Text PDFObjectives: Gastorenteropancreatic neuroendocrine (GEP-NET) tumors are the second most common tumors of the gastrointestinal tract. We aimed to investigate the clinicopathological features and factors affecting the prognosis of patients with GEP-NET.
Methods: Clinicopathological features of 158 patients were evaluated, including tumor location, TNM stage and grade, pathological features, presence of lymph nodes and distant metastases at the time of diagnosis, maximum tumor diameter and treatment details.
Objective: This study aims to explore the usage of intraocular pressure measurements as the early indicator of the increase in intra-abdominal pressure.
Methods: In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients.
Laparoscopic appendectomy for the neoplasm of the appendix remains a controversial subject in the literature. The main concern regarding laparoscopic treatment for the neoplasm of the appendix is incomplete resection and rupture of the tumor into the peritoneal cavity. There is a slight increase in the rate of invasion of the surgical margins in laparoscopic interventions.
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