Inclusion of fibrinoid necrosis increases the accuracy of synovial tissue assessment in predicting response to methotrexate: analysis of the UCLouvain Brussels ERA Cohort.

Objective: Rheumatoid Arthritis (RA) often exhibits suboptimal treatment response despite early diagnosis and treatment. This study aimed to analyze Early Rheumatoid Arthritis (ERA) synovial biopsies through histology and immunohistochemistry (IHC) to identify predictive factors for treatment response to Methotrexate (MTX).

Methods: 140 ERA patients from the UCLouvain Arthritis Cohort underwent synovial biopsy and were monitored after initiating Disease-Modifying Antirheumatic Drug (DMARD) therapy.

Psychiatric disorders in pregnancy.

The care and treatment of women with psychiatric disorders in pregnancy is both challenging and complex. The decision to treat or not treat can pose a risk to the mother, the developing fetus or infant and the pregnancy outcome. Treatment options can be both pharmacologic and non-pharmacologic.

Regionalization of perinatal care in Wisconsin: a changing health care environment.

Wisconsin has recently experienced a rapid increase in the number of neonatal intensive care units (NICUs), from 6 in the 1970s to 18 in 2003. Over the last year, the Wisconsin Association for Perinatal Care (WAPC) convened meetings in response to threats to regionalized care and worsening of perinatal outcomes, noted especially in some racial/ethnic groups. WAPC defined actions to address quality improvement, including adoption of designations for levels of care published by the American Academy of Pediatrics and the American College of Obstetricians and Gynecologists, definition of perinatal outcomes sensitive to quality of care, collection and analysis of outcome data, and continued statewide discussions about the status of regionalized care and outcomes.

The process of triage in perinatal settings: clinical and legal issues.

The process of triage in perinatal settings often has been considered the sole function of the labor and delivery nurse. In fact, all nurses have a legal and professional duty to engage in the systematic identification of patient-client problems, prioritization of needs, and prompt deployment of personnel and equipment to meet those needs. In-person and telephone triage occur in all obstetric ambulatory and acute care settings.