Publications by authors named "C Van Hoof"
Advancements in integrated circuit (IC) technology have accelerated the miniaturization of body-worn sensors and systems, enabling long-term health monitoring. Wearable electrocardiogram (ECG), finger photoplethysmogram (PPG), and wrist-worn PPG have shown great success and significantly improved life quality. Chest-based PPG has the potential to extract multiple vital signs but requires ultra-high dynamic range (DR) IC to read out the small PPG signal among large respiration and artifacts inherent in daily life.
View Article and Find Full Text PDFDynamic sub-array selection-based energy-efficient localization and tracking method to power implanted medical devices in scattering heterogenous media employing ultrasound.
IEEE Trans Biomed Circuits Syst
November 2024
Ultrasound (US) as a wireless power transfer methodology has drawn considerable attention from the implantable medical devices (IMD) research community. Beamforming (BF) using an external transducer array patch (ETAP) has been proposed as a robust localization scheme to find a mm-sized IMD inside the human body. However, for applications focusing on deep and shallow IMDs, optimum resource utilization at the ETAP is a major power efficiency concern for energy-constrained wearable patches.
View Article and Find Full Text PDFArticle Synopsis
- The World Health Organization recommends the use of single-dose rifampicin (SDR) for leprosy post-exposure prophylaxis (PEP), potentially reducing leprosy risk by about 50% in contacts of patients.
- A Phase 2 trial tested a new PEP regimen that combines bedaquiline with rifampicin (BE-PEP) against the standard therapy (SDR-PEP), focusing on safety and QT interval changes in patients.
- The trial, involving 313 participants, demonstrated that BE-PEP did not significantly differ from SDR-PEP regarding QT interval changes after treatment, indicating comparable safety profiles between the two regimens.
Article Synopsis
- - Anti-mycobacterial drugs can cause QT interval prolongation, risking serious heart issues, but monitoring is tough in places with high rates of leprosy and tuberculosis.
- - The BE-PEOPLE trial assessed the safety of a bedaquiline regimen while measuring QT intervals before and after treatment using both mobile electrocardiogram (mECG) and standard methods.
- - Results showed that mECG is a feasible and accurate tool for QT interval tracking, with a strong correlation to traditional measurements, although automated readings were generally less precise.
Background And Objectives: The number of people with dementia is expected to triple to 152 million in 2050, with 90% having accompanying behavioral and psychological symptoms (BPSD). Agitation is among the most critical BPSD and can lead to decreased quality of life for people with dementia and their caregivers. This study aims to explore objective quantification of agitation in people with dementia by analyzing the relationships between physiological and movement data from wearables and observational measures of agitation.
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