Publications by authors named "C V Ram"

Background: Solid pseudopapillary neoplasms (SPNs) arising in the body or tail of the pancreas can be amenable to laparoscopic distal pancreatectomy with or without concomitant splenectomy. The purpose of this study was to evaluate laparoscopic distal pancreatectomy for SPN using the Warshaw technique as a means to preserve spleens in children.

Methods: We reviewed our database of SPN patients 19 years and younger (January 2006-December 2023).

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Article Synopsis
  • - Specific gut microbes live in the mucin-rich layer of the gastrointestinal tract and can break down complex mucin glycoproteins for their own metabolism, affecting microbial interactions in the gut.
  • - A study created a synthetic community to analyze mucin degradation, showing that different mucin-degrading bacteria coexist and engage in cross-feeding, which leads to the production of beneficial metabolites like butyrate.
  • - Metaproteomics identified key bacteria responsible for mucin degradation and indicated that they adapt differently when grown in community settings versus alone, highlighting the complexity and interdependence of gut microbial interactions.
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Background and objectives In critically ill patients, acute kidney injury (AKI) influences mortality and morbidity. Few studies have looked at mortality and the frequency of AKI following successful heart and thoracic operations. The current study investigates the association between AKI and mortality rates among patients undergoing post-cardiac surgery care within the Cardiology & Cardio Vascular Thoracic Surgery (CVTS) Intensive Care Unit (ICU).

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Article Synopsis
  • Robotic surgery is transforming minimally invasive approaches, particularly benefiting pediatric surgeons through enhanced precision due to the small surgical areas involved.
  • A unique collaboration between pediatric and adult robotic surgeons facilitated the integration of robotic surgery in an academic setting, evaluating its outcomes against traditional laparoscopic techniques.
  • Results showed that robotic cholecystectomy (RC) is on par with laparoscopic cholecystectomy (LC) in key metrics like procedure duration and patient recovery, highlighting the feasibility and advantages of robotic surgery for pediatric patients.
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The human intestinal mucus layer protects against pathogenic microorganisms and harmful substances, whereas it also provides an important colonization niche for mutualistic microbes. The main functional components of mucus are heavily glycosylated proteins, called mucins. Mucins can be cleaved and utilized by intestinal microbes.

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