Aim: Chemotherapy-induced alopecia (CIA) is the most common side effect of systemic treatment in breast cancer patients. Scalp cooling gained worldwide acceptance in preventing or mitigating CIA in patients undergoing chemotherapy. The objective of this study was to evaluate the efficacy and safety of the Paxman scalp cooling system (PSCS) in Indian breast cancer patients.
View Article and Find Full Text PDFAshish Joshi The molecular characterization of advanced non-small-cell lung cancer (NSCLC) has unveiled genomic alterations such as gene mutations, gene mutations, gene rearrangements, rearrangements, and altered signaling. The objective of this molecular epidemiological study was to report the clinical, pathological, and molecular profile of NSCLC patients from western India. This real-world study of NSCLC patients was performed at a chemotherapy day-care center in western India.
View Article and Find Full Text PDFMetab Syndr Relat Disord
March 2008
Background: Limited information is available about the prevalence of the metabolic syndrome(MeTS) in India. Railway employees provided a unique opportunity to study the prevalence of MeTS in a variety of jobs.
Methods: A total of 995 railway employees, 872 males (mean age 42.
Cytokinin oxidase/dehydrogenase (CKO/CKX) is a flavoenzyme, which irreversibly inactivates cytokinins by severing the isoprenoid side chain from the adenine/adenosine moiety. There are several genes coding for the enzyme in maize (Zea mays). A Z.
View Article and Find Full Text PDFCytokinin oxidases (CKOs) play a major role in the regulation of hormone levels in plants by irreversibly degrading cytokinins. Two new cDNAs from maize (CKO2 and CKO3) were cloned and CKO activity of a recombinant CKO3 enzyme was demonstrated. CKO2 and CKO3 encode flavoproteins with 93% identity among each other compared with 45% identity with CKO1.
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