Publications by authors named "C V Okonkwo"
Introduction: Treatment of type 2 diabetes (T2D) remains a significant challenge because of its multifactorial nature and complex metabolic pathways. There is growing interest in finding new therapeutic targets that could lead to safer and more effective treatment options. Takeda G protein-coupled receptor 5 (TGR5) is a promising antidiabetic target that plays a key role in metabolic regulation, especially in glucose homeostasis and energy expenditure.
View Article and Find Full Text PDFThis study evaluated the long-term protective effect of gallic acid (GAL) against testicular lesions induced by busulfan (BUSLF) in Wistar rats. Thirty (30) male rats weighing 60-70 g were randomized into three groups of ten in each group: control (2 ml kg body weight (b.w) olive oil), BUSLF (10 mg kg b.
View Article and Find Full Text PDFMost developing countries are currently experiencing a severe food security crisis. A good policy to mitigate food insecurity is dependent on accurate assessment. Therefore, an improved assessment of food situation is important in implementing food security measures.
View Article and Find Full Text PDFArticle Synopsis
- The study developed hydrophobic stainless steel meshes for effective recovery of ABE (acetone, butanol, and ethanol) from bioreactors during vacuum-assisted gas stripping, minimizing water loss.
- Three types of meshes with varying pore sizes (180 µm, 300 µm, and 425 µm) were coated with zinc oxide and polydimethylsiloxane, showing that the 180-µm mesh retained significantly more water (54-65% more) compared to uncoated ones.
- The technology increased butanol concentration in recoveries by up to 10.8-fold and proved effective for real-time ABE extraction from lignocellulosic fermentation without clogging issues.
Background: The health workplace is fraught with fluctuations and uncertainties, creating a volatile, uncertain, complex, and ambiguous (VUCA) environment, particularly impacting frontline healthcare workers (HCWs) and leading to an epidemic of stress, burnout and health issues, exacerbated by the COVID-19 pandemic.
Objectives: This paper aims to explore the multifaceted aspects of HCWs wellbeing, address challenges arising due to COVID-19 and VUCA and highlight innovative approaches within health systems to enhance the quality of life HCWs.
Methods: A systematic review was conducted using PubMed and Scopus with search terms including 'VUCA,' 'health personnel,' 'frontline healthcare workers,' and 'psychological wellbeing.