Publications by authors named "C V Matula"
Objective: Excessively prescribed opioids promote chronic drug abuse and worsen a highly prevalent public health problem in the era of the opioid epidemic. This study aimed to (a) determine general analgesic prescription patterns after surgery for vestibular schwannoma (VS) with a focus on opioid prescription rates, (b) identify risk factors for receiving narcotics for postoperative pain management, and (c) highlight the feasibility of opioid-free analgesic treatment strategies.
Study Design: Retrospective chart review.
Declaration of Computational Neurosurgery.
Adv Exp Med Biol
November 2024
Computational neurosurgery is a novel and disruptive field where artificial intelligence and computational modeling are used to improve the diagnosis, treatment, and prognosis of patients affected by diseases of neurosurgical relevance. The field aims to bring new knowledge to clinical neurosciences and inform on the profound questions related to the human brain by applying augmented intelligence, where the power of artificial intelligence and computational inference can enhance human expertise. This transformative field requires the articulation of ethical considerations that will enable scientists, engineers, and clinical neuroscientists, including neurosurgeons, to ensure that the use of such a powerful application is conducted based on the highest moral and ethical standards with a patient-centric approach to predict and prevent mistakes.
View Article and Find Full Text PDFObjective: To evaluate the long-term hearing outcome after translabyrinthine resection of tumors within the internal auditory canal (IAC) with simultaneous cochlear implantation (CI).
Study Design: Prospective study.
Setting: Tertiary referral center.
Article Synopsis
- The study looked at how to safely position patients during a special type of brain surgery to prevent dangerous air bubbles in the blood.
- Researchers checked the medical records of 202 patients who had this surgery in a sitting position between 2019 and 2022.
- They found that about 15% had air bubbles, but most cases were not serious, and being taller or having a lower health risk was linked to a higher chance of bubbles forming.
Objective: Determining the concentration of prestin in human blood, cerebrospinal fluid (CSF), and perilymph (PL), and evaluating its suitability as a clinical biomarker for sensori-neural hearing loss (SNHL).
Study Design: Human blood, CSF, and PL samples were intraoperatively collected from 42 patients with tumors of the internal auditory canal or with intracochlear tumors undergoing translabyrinthine or middle fossa tumor removal. Prestin concentration was measured using enzyme-linked immunosorbent assay and linear regression analyses were performed to investigate its associations with audiological as well as vestibular test results.