A cationic main-chain poly(carbonate-imidazolium) potent against Mycobacterium abscessus and other resistant bacteria in mice.

The incidence of serious lung infections due to Mycobacterium abscessus, a worrying non-tuberculosis mycobacteria (NTM) species, is rising and has in some countries surpassed tuberculosis. NTM are ubiquitous in the environment and can cause serious lung infections in people who are immunocompromised or have pre-existing lung conditions. M.

Emerging solid-state cycloaddition chemistry for molecular solar thermal energy storage.

Recently discovered designs of solid-state molecular solar thermal energy storage systems are illustrated, including alkenes, imines, and anthracenes that undergo reversible [2 + 2] and [4 + 4] photocycloadditions for photon energy storage and release. The energy storage densities of various molecular designs, from 6 kJ mol to 146 kJ mol (or up to 318 J g), are compared and summarized, along with effective strategies for engineering their crystal packing structures that facilitate solid-state reactions. Many promising molecular scaffolds introduced here highlight the potential for achieving successful solid-state solar energy storage, guiding further discoveries and the development of new molecular systems for applications in solid-state solar thermal batteries.

Rh(III)-Catalyzed Chemoselective [4 + 2] Annulations for the Synthesis of [1,3]Oxazinoindolones: A Combined Experimental and Computational Study.

The interaction of -alkoxy-1-indole-1-carboxamides with transition metals leads to indole-fused heterocyclic scaffolds through directing group leaving/migration, [3 + 2], N-C2 [4 + 1], and [4 + 2] annulations. However, the corresponding O-C2 [4 + 2] annulation reactions have never been reported. Herein, we report the chemoselective annulation of -alkoxy-1-indole-1-carboxamides catalyzed by Rh(III), affording [1,3]oxazinoindolones through a hitherto unknown reaction pathway.

Synthesis and dengue inhibition potential of new uridine derivatives: The DENV 2 inhibitors.

Dengue is an important arboviral infection worldwide for which presently there is no specific medicine. Evidence suggests there are four serotypes of dengue virus (DENV1-4), of which DENV 2 is considered to cause the most sever dengue. Therefore, this study was aimed to develop the new uridine derivatives (NUDs) against dengue virus (DENV 2).

Computer Vision-Assisted Robotized Sampling of Volatile Organic Compounds.

In conventional chemical analysis, samples are homogenized, extracted, purified, and injected into an analytical instrument manually or with a certain degree of automation. Such complex methods can provide superior performance in terms of sensitivity or selectivity. However, in some cases, it would be advantageous to possess a method that circumvents those preparatory steps, which require much attention.