Effects of Speed-Based Interventions to Reduce Bradykinesia in Individuals with Parkinson's Disease: A Systematic Review Protocol.

Background/objectives: Bradykinesia is considered one of the most disabling motor symptoms in individuals with Parkinson's disease (PD). Speed-based interventions are promising for reducing bradykinesia in this population. This systematic review aims to describe speed-based interventions that have been employed for reducing bradykinesia in individuals with PD and verify their effects.

Prevalence of sensory impairments and its contribution to functional disability in individuals with acute stroke: A cross-sectional study.

Background: Although the literature suggests high prevalences of sensory impairments after stroke, the independent contribution of sensory modalities to functionality needs further investigation.

Objective: To identify the prevalence and characterize the sensory impairment in adults with stroke and to verify the contribution of proprioceptive and exteroceptive impairments to their functional disability.

Methods: Exploratory cross-sectional study conducted in a hospital stroke unit.

Emergence of in Minas Gerais, Brazil: Genomic Surveillance to inform Rapid Public Health Responses.

poses a significant global health threat due to its multidrug-resistance and outbreak potential. In this study, we report its emergence in Minas Gerais, Brazil, supported by genomic surveillance that identified Clade-IV isolates, suggested a potential introduction from Colombia, and detected a missense mutation associated with azole resistance.

Stroke in Brazil: prevalence, activity limitations, access to healthcare, and physiotherapeutic treatment.

Background:  Stroke remains a public health problem, reported as the third cause of disability. Among survivors, the ability to perform usual daily activities may be reduced, requiring rehabilitation.

Objective:  To investigate the prevalence of self-reported stroke, the accessibility of healthcare, and the degree and percentage of patients with limitations in usual activities who are unassisted by physiotherapeutic treatment in different regions of the country.

Trazodone-gabapentin association increases sedation scores with mild hemodynamic and echocardiographic impact in healthy cats.

Despite the increasing use of drugs to facilitate feline management in veterinary care, there is still a lack of information on the anxiolytic and sedative effects and their specific physiological impacts. We aimed to compare the sedative, hematological, biochemical and cardiovascular effects of oral single-dose trazodone and gabapentin, alone or in combination, in 8 healthy adult mixed-breed domestic cats on a prospective, randomized, cross-over, and placebo-controlled study. Cats were assigned to receive an oral single dose of trazodone (50 mg) (TG), gabapentin (100 mg) (GG), trazodone (50 mg) and gabapentin (100 mg) (GTG), or placebo (PG).