Publications by authors named "C V Cardemil"
Background: Following maternal COVID-19 vaccination, the persistence of antibodies in sera and breast milk for mothers and infants is not well characterized. We sought to describe the persistence of antibodies through 2 months after delivery in maternal and infant serum and breast milk following maternal COVID-19 mRNA vaccination and to examine differences by receipt of booster dose during pregnancy or postpartum.
Methods: This is a prospective cohort study with enrollment from July 2021 to January 2022 at 9 US academic sites.
Purpose: Primary chronic osteomyelitis (PCO) of the jaw is a non-infectious, inflammatory state of the jawbone of unknown etiology. This study aimed to investigate the occurrence of PCO in Sweden between the years 2012 and 2018, the characteristics of the condition, treatment methods, and outcomes. Material and methods: The search for patients with PCO in Sweden 2012-2018 was performed at 24 oral and maxillofacial surgery units in Sweden.
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- Maternal vaccination with mRNA COVID-19 vaccines can help protect infants from COVID-19 by passing antibodies through the placenta during pregnancy.
- Infants born to mothers who received a booster shot had higher levels of protective antibodies and were 56% less likely to contract COVID-19 in their first 6 months compared to those whose mothers did not receive a booster.
- The study suggests that higher antibody levels at delivery reduce infection risk significantly, emphasizing the importance of maternal vaccination until infants can be vaccinated themselves.
Background: While prior studies have suggested a role for norovirus gastroenteritis in contributing to severe morbidity and mortality, the importance of norovirus as a causal pathogen for hospitalization and mortality remains poorly understood. We estimated the effect of laboratory-confirmed norovirus infection on hospitalization and mortality among a national cohort of veterans who sought care within the Veterans Affairs health care system.
Methods: We analyzed electronic health record data from a cohort study of adults who were tested for norovirus within the Veterans Affairs system between 1 January 2010 and 31 December 2018.
Article Synopsis
- A multicenter study analyzed the immune responses to COVID-19 vaccinations in pregnant women, focusing on both primary doses and boosters from July 2021 to January 2022.
- Results showed that booster vaccinations led to significantly higher antibody levels in mothers and their newborns, particularly against the Omicron BA.1 variant, compared to those who received only the primary 2-dose series.
- Efficient transplacental antibody transfer was observed for all vaccination regimens, indicating robust immune responses in mothers and effective protection for infants.