Computational Models-Based Detection of Peripheral Malarial Parasites in Blood Smears.

The most common human parasite as per the medical experts is the malarial disease, which is caused by a protozoan parasite, and Plasmodium falciparum, a common parasite in humans. A microscopist with expertise in malaria diagnosis must conduct this complex procedure to identify the stages of infection. This epidemic is an ongoing disease in some parts of the world, which is commonly found.

Label-free detection of cupric ions and histidine-tagged proteins using single poly(pyrrole)-NTA chelator conducting polymer nanotube chemiresistive sensor.

Novel chemical and biological sensors based on a single poly(pyrrole)-NTA chelator nanotube for sensitive, selective, rapid and real-time detection of histidine-tagged protein and cupric ions are reported. NTA groups on the nanotube surface provided a simple mechanism for metal ion sensing via the high-affinity interaction between NTA and the subsequent detection of histidine-tagged protein through the coordination with metal chelated nanotube. Poly(pyrrole)-NTA chelator nanotubes of 190 nm outside diameter, 35 nm wall thickness and 30 microm long were synthesized by electrochemical polymerization of pyrrole-NTA inside a 200 nm diameter alumina template and assembled as a chemoresistive device by bottom-up contact geometry on a pair of parallel gold electrodes with a gap distance of 3 microm.