Publications by authors named "C Urbanek"
Aims: Atrial fibrillation (AF) accounts for about 20% of all ischemic strokes worldwide. It is known that AF impairs health-related quality of life (HRQOL) in the general population, but data on HRQOL in stroke patients with newly diagnosed AF are sparse.
Methods: Post hoc analysis of the prospective, investigator-initiated, multicenter MonDAFIS study (NCT02204267) to analyze whether AF-related oral anticoagulation (OAC), and/or AF-symptom severity are associated with HRQOL after ischemic stroke or transient ischemic attack (TIA).
Introduction: Intravenous thrombolysis (IVT) is an on label treatment for selected patients with acute ischemic stroke (AIS). As major bleeding or allergic shock may occur, the need to ensure patients' informed consent for IVT is a matter of debate.
Patients And Methods: Prospective investigator-initiated multi-center observational study to assess the ability of AIS patients to recall information, provided by a physician during a standardized educational talk (SET) on IVT use.
Purpose: This study aimed at comparing clinical outcome, recanalization success and time metrics in the "drip and ship" (DS) vs. "drive the doctor" (DD) concept in a comparable setting.
Methods: This is a retrospective analysis of thrombectomy registries of a comprehensive stroke center (CSC) and a thrombectomy-capable stroke center (TSC).
Article Synopsis
- High levels of antibodies against glutamic acid decarboxylase (GAD-abs) are linked to various autoimmune neurological syndromes, while the significance of low serum levels is still debated.
- A study analyzed data from 101 patients suspected of having GAD-ab-associated neurological issues, revealing that most presented with conditions like epilepsy and cerebellar ataxia but had mixed outcomes with immunotherapy.
- The research found that low GAD-ab serum levels didn't significantly affect clinical characteristics or outcomes, suggesting that detecting unmatched oligoclonal bands in the cerebrospinal fluid may be more important than GAD-ab levels.
Seizure Semiology in Antibody-Associated Autoimmune Encephalitis.
Neurol Neuroimmunol Neuroinflamm
November 2022
Article Synopsis
- - The study evaluates seizure characteristics in patients with antibody-associated autoimmune encephalitis (ab + AE) focusing on the three most common antibodies: NMDAR, LGI1, and GAD, involving 320 patients across multiple centers in Germany.
- - Seizures were prevalent in these patients, with frequencies of 60% in NMDAR+, 78% in LGI1+, and 65% in GAD+, and certain types of seizures such as faciobrachial dystonic seizures and status epilepticus presented uniquely or more frequently in specific antibody groups.
- - The findings suggest that seizure types can help in diagnosis, with distinct patterns observed among different antibodies, indicating that NMDAR+ patients tend to have