Publications by authors named "C Uneyama"

Some countries have conducted a total diet study (TDS) focused on the estimation of specific trace elements. Although some results of a Japanese TDS examining trace elements were published, there have been no reports of a nationwide TDS across Japan over a multi-year period to estimate the level of exposure to multiple elements. In the present study, a TDS using a market basket approach was performed to estimate the dietary exposure levels of the general population of Japan to 15 elements, including aluminum (Al), total arsenic (tAs), boron (B), barium (Ba), cadmium (Cd), cobalt (Co), chromium (Cr), total mercury (THg), molybdenum (Mo), nickel (Ni), lead (Pb), antimony (Sb), selenium (Se), tin (Sn), and uranium (U).

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Dietary intake of methylmercury from fish was estimated via Monte Carlo simulation using data for methylmercury concentrations in 210 fish samples and data regarding fish consumption extracted from the Japanese National Health and Nutrition Survey. The fish analyzed were classified into 5 groups according to categories used in the survey. The distribution of consumption of fish from each group was used without fitting to statistical distributions.

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Article Synopsis
  • Total Diet Study (TDS) is important for estimating dietary intake of hazardous substances, with guidance from the WHO on method validation.
  • Despite various guidelines, clear procedures for confirming method validity are still lacking.
  • This study introduced SEMPs to test analytical methods for measuring elements like arsenic and lead, establishing a performance evaluation through repeated analysis of both fortified and non-fortified samples.
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Article Synopsis
  • Consumer interest in health foods has surged, leading to a rapid expansion of the market but raising significant safety concerns due to reported adverse events.
  • Serious health issues, including liver and renal failure, as well as death, have been linked to certain health foods that may contain harmful undeclared ingredients or natural toxins.
  • The paper examines regulatory practices and incidents of adverse effects from health foods in various countries, highlighting cases like "OxyElite Pro," which has been linked to liver failure and other health problems in users.
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