Publications by authors named "C Tsonidis"

: Endoscopic third ventriculostomy (ETV) is an effective treatment for hydrocephalus. The in-depth understanding of microanatomy is essential for accurate diagnosis, treatment and complications prevention. The aim of this study is to supplement the knowledge gap regarding the microanatomical metrics and correlations for which the literature includes only scarce mentions at best.

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Article Synopsis
  • - The study aimed to compare the Full Outline of Unresponsiveness (FOUR) Score and the Glasgow Coma Scale (GCS) in predicting patient outcomes regarding consciousness, regardless of the raters' experience.
  • - Data was collected from 86 patients in Neurosurgery and Intensive Care, and both scales performed excellently in predicting mortality and poor outcomes, with no significant differences in effectiveness between them.
  • - Results showed that both scoring systems are reliable for assessing short- and long-term patient outcomes, and even inexperienced raters could use the FOUR Score effectively without compromising accuracy.
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Background And Purpose: According to the classical hypothesis, the cerebrospinal fluid (CSF) is actively secreted inside the brain's ventricular system, predominantly by the choroid plexuses, before flowing unidirectionally in a cranio-caudal orientation toward the arachnoid granulations (AGs), where it is reabsorbed into the dural venous sinuses. This concept has been accepted as a doctrine for more than 100 years and was subjected only to minor modifications. Its inability to provide an adequate explanation to questions arising from the everyday clinical practice, in addition to the ever growing pool of experimental data contradicting it, has led to the identification of its limitations.

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Objectives: Although the Reaction Level Scale (RLS) is still used for the assessment of the level of consciousness in distinct centers, its clinical characteristics and significance have been incompletely researched. In the current study, the clinimetric properties, the prognostic value, and the impact of the raters' background on the application of the RLS, in comparison with the Glasgow Coma Scale (GCS), are investigated.

Materials And Methods: A systematic review on the available clinical evidence for the RLS was first carried out.

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Objectives: There is limited data on the direct clinical comparison between short and long fusion following surgery for lumbar spinal stenosis. The hypothesis that regardless their baseline characteristics and morbidity, clinical outcome is similar in patients with lumbar stenosis treated with decompression plus posterior instrumented fusion in one or two versus three to five levels was tested.

Methods: Subjects were divided into Group A and Group B corresponding to stenotic pathology and instrumented fusion in one or two levels and three to five levels, respectively.

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