Publications by authors named "C Trottier"

Background: A subgroup of patients with chronic pelvic pain (CPP) exhibit organ sensitization, whose origin and mechanism remains largely unknown. Changes in microbiota composition in pelvic organs have been found to be associated with various pelvic pathological conditions. Therefore, a comprehensive analysis of the gut and genito-urinary microbiota composition and interactions in women with CPP may be key to understanding their involvement in the sensitization processes.

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Despite increasing utilization of CAR T-cell therapy, data are lacking regarding long term follow up and risk of infectious complications after the early period following CAR T-cell infusion. In this study, we sought to compare epidemiology and risk factors for early (≤ 3 months) and late (3 months to 1 year) infections. Data were retrospectively collected at six time points: pre-CAR T, day of infusion, and at 3, 6, 9, and 12 months post CAR-T infusion for all consecutive adult patients treated at our institution.

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Article Synopsis
  • Infections after orthotopic heart transplantation (OHT) can lead to serious health issues, prompting a study to evaluate the impact of different types of mechanical circulatory support (MCS) before surgery.
  • Researchers analyzed data from 320 OHT patients at Tufts Medical Center between 2014 and 2022, focusing on the risk of various infections within a year post-transplant based on whether patients received temporary or durable MCS pre-surgery.
  • The findings showed that there was no significant difference in the time to first infection between those who received temporary MCS and those with durable MCS, suggesting that the type of MCS used before OHT may not influence post-operative infection rates.
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  • Excess body weight and other lifestyle factors like diet, inactivity, and stress are linked to chronic diseases, but can be modified through digital interventions.
  • The DIRECTION study tests the effectiveness of adding healthcare guidance and peer support to an online wellness platform compared to self-guided use among individuals considered obese.
  • Over 16 weeks, the experimental group participates in daily platform use and weekly support sessions, with outcomes focused on weight loss, dietary habits, physical activity, and changes in health-related behaviors.
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Background: Low muscle mass (MM) predicts unfavorable outcomes in cancer. Protein intake supports muscle health, but oncologic recommendations are not well characterized. The objectives of this study were to evaluate the feasibility of dietary change to attain 1.

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