Publications by authors named "C Travis Powell"

Background: Therapeutic plasma exchange (TPE) is the primary intervention for treating symptomatic hyperviscosity from hypergammaglobulinemia, yet its efficacy for treating hyperviscosity related to hyperfibrinogenemia is unclear.

Objective: Define the safety and efficacy of TPE for critically ill COVID-19 patients with elevated blood viscosity from hyperfibrinogenemia.

Method: A prospective, randomized controlled trial in critically ill COVID-19 patients at a single US healthcare system.

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Article Synopsis
  • This study aimed to explore how demographic factors and measurements of nonperfusion (NP) and neovascularization (NV) on ultra-widefield fluorescein angiography relate to intravitreal injections (IVIs) and panretinal photocoagulation (PRP) treatment in diabetic patients.
  • It included 363 diabetic patients treated at the University of Michigan, analyzing the effectiveness of these treatments based on retinal image data from 2009 to 2018 while excluding those with previous PRP treatment or poor image quality.
  • Results revealed that higher NP and NV areas were associated with increased IVIs and PRP treatments, and type 2 diabetes was linked to a greater risk of progression in diabetic retinopathy compared to type 1
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This study examines the impact of two types of environmental enrichment on the growth of the Amazon molly (), a clonal fish species. We investigated the effects of two welfare-related enrichment factors: physical enrichment (presence of a halfpipe PVC and gravel substrate, E) and social enrichment (presence of visible neighbor fish, N). Fish were divided into four treatment groups: (1) both physical and social enrichment (EN), (2) no physical enrichment but social enrichment (nEN), (3) physical enrichment without social enrichment (EnN,), and (4) no enrichment (nEnN).

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Small intestine neuroendocrine tumours (SI-NETs) are often diagnosed late with a UK median of 3 years and high misdiagnosis rates. Previous studies, largely based on patient surveys, offer little data on improving diagnosis. In 2017, the South Wales NET service underwent a nationally commissioned, systematic transformation, aiming to improve diagnosis through the development of a gastroenterology and surgical referral network, and education of these specialities.

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Rationale & Objective: Chronic kidney disease affects millions of people in the United States, yet effective interventions to address gaps in patient knowledge and engagement are not well established. We sought to develop and pilot a brief educational decision aid for patients with CKD cared for in primary care settings.

Study Design: A pilot QI study of a decision aid intervention.

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