Publications by authors named "C Trang-Poisson"
Article Synopsis
- This pilot study aimed to see if confocal laser endoscopy (CLE) can help identify certain cells (α4β7- and TNF-expressing) that could predict how well ulcerative colitis patients respond to the drug vedolizumab.
- Nineteen patients with moderate-to-severe ulcerative colitis participated, and 58% showed clinical and endoscopic improvement after treatment, with specific staining patterns indicating potential responders versus non-responders.
- The findings suggest that positive α4β7 staining detected through CLE could be linked to better treatment outcomes, although blood tests and immune cell counts did not correlate with patient responses.
Article Synopsis
- Patients with inflammatory bowel disease (IBD) treated with infliximab or vedolizumab showed a COVID-19 prevalence similar to the general French population before vaccinations, with only 4.5% confirmed cases.
- Factors increasing COVID-19 risk included using public transport and living in urban settings, while treatment type or disease activity did not affect infection rates.
- Recommendations suggest that maintaining sanitary barrier measures is essential for IBD patients on biological therapies to minimize the risk of SARS-CoV-2 infection.
Background: The impact of inflammatory bowel disease (IBD) on caregivers has rarely been investigated. Our work aims to explore the burden of IBD on the different aspects of caregivers' lives.
Methods: We conducted an online survey via the social network of the French IBD patient organization addressed to patients' caregivers who were asked to fill in a questionnaire covering the impact of the disease on different aspects of their lives.
Background And Objective: Anti-TNFs have been shown to significantly improve the health-related quality of life (HRQoL) in Crohn's disease (CD) patients. The purpose of this study was to investigate to what extend the patients' preferences for these intravenous (IV) and subcutaneous (SC) treatments differ based on respondents' quality of life. An online discrete choice experiment (DCE) was conducted to understand patient trade-offs in treatment choice.
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