Duplicated genes are thought to follow one of three evolutionary trajectories that resolve their redundancy: neofunctionalization, subfunctionalization, or pseudogenization. Differences in expression patterns have been documented for many duplicated gene pairs and interpreted as evidence of subfunctionalization and a loss of redundancy. However, little is known about the functional impact of such differences and about their molecular basis.
View Article and Find Full Text PDFBackground: Low vaccination rates against influenza and Streptococcus (S.) pneumoniae infections in COPD could impair outcomes. Understanding underlying factors could help improving implementation.
View Article and Find Full Text PDFStudying the independent evolution of similar traits provides valuable insights into the ecological and genetic factors driving phenotypic evolution. The transition from outcrossing to self-fertilization is common in plant evolution and is often associated with a reduction in floral attractive features such as display size, chemical signals, and pollinator rewards. These changes are believed to result from the reallocation of the resources used for building attractive flowers, as the need to attract pollinators decreases.
View Article and Find Full Text PDFNeckar River virus (NRV), first isolated from a water sample of the Neckar River (Germany) in the 1980s, was serologically characterized as a novel tombusvirus. In this study, the complete genome sequence was determined, and an infectious full-length cDNA clone was constructed. The genome organization of NRV (DSMZ PV-0270) resembles that of tombusviruses.
View Article and Find Full Text PDFIn a recent issue of Nature, Huang et al. identify and show how to overcome the barriers to successful pollen germination after interspecific crosses. Their findings answer a long-standing question about reproductive barriers in flowering plants and open the door to harnessing genetic diversity of distant relatives for crop improvement.
View Article and Find Full Text PDF