Publications by authors named "C Toure-Kane"
Background: Expanding antiviral therapy to people with chronic hepatitis B virus (HBV) infection who are ineligible to receive treatment under current international criteria has been increasingly debated. Evidence to support this approach is scarce, especially in Africa. We aimed to address this knowledge gap by analysing the clinical outcomes of people with chronic hepatitis B in The Gambia who were untreated and ineligible for antiviral therapy at diagnosis.
View Article and Find Full Text PDFBackground: In endemic areas, vertical transmission of hepatitis B virus (HBV) remains a major source of the global reservoir of infected people. Eliminating mother-to-child transmission (MTCT) of HBV is at the heart of World Health Organization's goal of reducing the incidence of HBV in children to less than 0.1% by 2030.
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- In Senegal, molecular diagnosis for COVID-19 was effective, but genomic surveillance in the public sector was limited.
- The study analyzed 8,207 samples from travelers and symptomatic patients between July 2020 and December 2021, identifying a significant number of SARS-CoV-2 variants through whole-genome sequencing.
- Results showed that 20A and 20B variants circulated in 2020, while Delta variants were predominant in 2021, highlighting the global trend in viral diversity during the pandemic.
Natural spices play an essential role in human nutrition and well-being. However, their processing on different scales can expose them to potential sources of contamination. This study aimed to describe the bacterial community genomic footprint in spices sold in Senegal.
View Article and Find Full Text PDFBackground: Due to the low number of individuals with HIV-2, no randomised trials of HIV-2 treatment have ever been done. We hypothesised that a non-comparative study describing the outcomes of several antiretroviral therapy (ART) regimens in parallel groups would improve understanding of how differences between HIV-1 and HIV-2 might lead to different therapeutic approaches.
Methods: This pilot, phase 2, non-comparative, open-label, randomised controlled trial was done in Burkina Faso, Côte d'Ivoire, Senegal, and Togo.