Publications by authors named "C Tie"
Transcranial focused ultrasound stimulation (tFUS) has emerged as a promising therapeutic strategy for mitigating brain injury in animal models. In this study, the effects and mechanisms of tFUS on ischemic stroke were explored in a transient middle cerebral artery occlusion (MCAO) rat model. Low-intensity tFUS was administered to the ischemic hemisphere 24 h post-MCAO for seven consecutive days.
View Article and Find Full Text PDFLipid peroxidation plays an important role in physiological and pathophysiological conditions; it occurs mainly in the vicinity of the membrane. Glycerophospholipids are indispensable for normal structure of membranes. Lipid mediators are final products of lipid peroxidation.
View Article and Find Full Text PDFBackground: During the development of disease-modifying intervertebral disc degeneration (IDD) drugs, the rat model of IDD is frequently used for disease progression assessment. The aim of this study was to describe a magnetic resonance (MRI) scoring system for the assessment of different disc conditions in puncture-induced IDD, allowing standardization and comparison of results obtained by different investigators.
Methods: A total of 36 Sprague-Dawley rats were utilized in the present study.
Atmospheric ozone (O) has been placed on the priority control pollutant list in China's 14th Five-Year Plan. Due to their unique meteorological conditions, plateau regions contain high concentrations of atmospheric O. However, traditional experimental methods for determining O concentrations using automatic monitoring stations cannot predict O trends.
View Article and Find Full Text PDFArticle Synopsis
- The brain-computer interface (BCI) is crucial for advancing neuroscience and understanding brain functions, with non-invasive neuromodulation techniques playing a key role in innovations.
- Researchers developed a new non-invasive closed-loop acoustic BCI (aBCI) that uses electroencephalography (EEG) to detect seizures and employs ultrasound to stimulate the vagus nerve, effectively stopping seizures in a rat model.
- The aBCI selectively targets mechanosensitive neurons in the vagus nerve, shows significant effectiveness over conventional methods, and offers a promising and safe option for treating seizure disorders non-invasively.