Publications by authors named "C Theresa"

Severe acute coronavirus-2 (SARS-CoV-2) infection has been associated with endothelial damage, and impaired nitric oxide production, which results in arterial stiffness and increased risk of cardiovascular disease. Long COVID is a term used to describe the persistence or the development of new symptoms that can occur after an acute infection. Little is known about the association between arterial stiffness and Long COVID.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluates the impact of adding Valproic Acid (VPA), an antiepileptic drug with histone deacetylase inhibitor properties, to standard radiation and temozolomide treatments in patients with glioblastoma (GBM), as compared to historical data from standard care protocols.* -
  • A total of 37 patients participated in the phase II trial, which demonstrated improved median overall survival (OS) of 30.9 months and progression-free survival (PFS) of 11.1 months, significantly better than the 18.9 months OS and 7.5 months PFS seen in the RTOG 0525 study.* -
  • Key factors influencing survival outcomes included
View Article and Find Full Text PDF

Background: Tobacco smoke is harmful to health. In the acute phase it causes changes in the cardiovascular system that result in an increase in blood pressure (BP). An increase in arterial stiffness due to arteriolar endothelial dysfunction has been cited among the causes.

View Article and Find Full Text PDF

Adriamycin containing combination chemotherapy (ACCC) is usually delivered to patients with stages III, IV diffuse large cell (DLCL) non-Hodgkin's lymphoma (NHL). Although this mode of therapy is also commonly used in other intermediate grade lymphomas, it's role in the latter subset of patients is not well defined. In a retrospective analysis we evaluated and compared the outcome of previously untreated DLCL and non-DLCL intermediate grade lymphoma patients who received as initial therapy, "first generation" ACCC.

View Article and Find Full Text PDF