Publications by authors named "C Ten Thoren"

Background: In 2009 the journal WORK commenced a new column for the publication of Work Transition Narratives. Fourteen persons with lived experience published their narratives on approaches that helped them through work disruptions and change.

Objective: A review of the articles was conducted to understand how people navigated challenges and obstacles and made sense of their in-transition experiences to return to work or to find new employment.

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Objectives: Dossiers submitted for early benefit assessments in Germany also provide information on the precise determination of the target population (patients eligible for a drug). The situation is complex for non-small-cell lung cancer (NSCLC) due to highly specific therapeutic indications. Our aim was to compare the different methodological steps applied to determine the target population in dossiers on drugs for NSCLC.

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Objectives: Since 2011, early benefit assessment of all new drugs launched in Germany is mandatory. The exact determination of the appropriate target population (i. e.

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Article Synopsis
  • * Development of the efficiency frontier approach was necessary to meet legal requirements, but ongoing health care reforms and changing objectives have altered the landscape.
  • * Current drug price negotiations depend on early benefit assessments from pharmaceutical companies, raising questions about the SHI system’s sustainability and its need to utilize health economic evaluations for various interventions.
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